Carboplatin CAS NO.41575-94-4

Min.Order: 1 Gram
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Product Details

Keywords

Carboplatin
Carboplatin
41575-94-4

Quick Details

ProName: Carboplatin
CasNo: 41575-94-4
Molecular Formula: C6H12N2O4Pt
Appearance: white to almost white powder
Application: anticancer
DeliveryTime: prompt
PackAge: 1kg/drum
Port: shanghai/beijing
ProductionCapacity: 10000 Metric Ton/Day
Purity: 99
Storage: low temperature
Transportation: sea/air/courier
LimitNum: 1 Gram

Superiority

Product name: Carboplatin

Molecular formula : C6H12N2O4Pt

CAS Registry Number : 41575-94-4

Standard: USP35/EP7

Appearance: White crystalline powder

Purpose: Anticancer drugs

Details

Carboplatin

Name:

1,1-Cyclobutanedicarboxylatodiammineplatinum (II)

EINECS:

255-446-0

Molecular Formula:

C6H12N2O4Pt

CAS No: 41575-94-4

Synonyms:

diammine(1,1-cyclobutanedicarboxylato)-platinum(I; Carboplatin; 1,1-Cyclobutanedicarboxylate diamine platinum(II); Paraplatin; CBDCA; cis-(1,1-Cyclobutanedicarboxylato)diamineplatinum(II); cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II); Platinum, diamine(1,1-cyclobutanedicarboxylato(2-)-O,O')-,(SP-4-2)-; 1,1-Cyclobutanedicarboxylatodiammineplatinum

InChI:

InChI=1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2

Molecular Structure:

Chemical Properties

Appearance: white crystalline powder

Molecular Weight: 373.26436

Boiling Point: 366.4oCat 760 mmHg

Melting Point: 228-230oC

Flash Point: 189.6oC

Solubility: Soluble

Biological Activity:

Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and displays lower nephrotoxicity than analog cisplatin (cis-Diaminodichloroplatinum ).

Stability: Stable. Incompatible with strong oxidizing agents.

Usage: Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic

Safety Data of 41575-94-4

Safety Statements: S53;S22;S26;S36/37/39;S45

MSDS infomation: 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) (41575-94-4).msds

Items	Acceptance Criteria	Result
Appearance	White crystalline powder	White crystalline powder
Solubility	Sparing soluble in water,very slightly soluble in acetone and ethanol	Conforms
mp	About 200℃	200.5
IR	Consistent with reference standard	Conforms
Appearance of solution	Clear and colorless	Conforms
Impurity B and acidicy	Impurity B NMT 0.5% Acidify :meet requirement	Conforms
Related substance	Impurity A NMT 0.5%	N.D.
	Any other impurity NMT 0.25%	0.03%
	Total impurity NMT0.5%	0.03%
Chlorides	NMT100ppm	Conforms
Ammonium	NMT 100ppm	Conforms
Heavy metal	NMT20ppm	Conforms
Soluble Barium	NMT10ppm	Conforms
Loss on drying	NMT0.5%	0.13%
Assay	98.0%~102%	99.5%
pH	5.0~7.0	6.2
Water	NMT0.5%	0.12
Transmittance	MT97%	97.9%
Water-insoluble matter	NMT 0.5%	0.15%
1,1-cyclobutanedicarboxylic acid	NMT0.25%	0.03%
Residual solvents	Aether NMT 500ppm	2ppm
Residual solvents	Ethanol NMT500ppm	40ppm
Platinum	52.0%~53.0%	52.5%
Bacterial Endotoxins	NMT 0.12EU/mg	Conforms