China (Mainland)
Febuxostat CAS NO.144060-53-7
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,
- Product Details
Keywords
- 144060-53-7
- Febuxostat
- febuxostat
Quick Details
- ProName: Febuxostat
- CasNo: 144060-53-7
- Molecular Formula: C16H16N2O3S
- Appearance: White crystalline powder, odorless
- Application: API
- DeliveryTime: prompt
- PackAge: 25kg/drum
- Port: shanghai/beijing/qingdao
- ProductionCapacity: 10000 Metric Ton/Month
- Purity: 99%
- Storage: tight container
- Transportation: sea/air/courier
- LimitNum: 1 Kilogram
Superiority
| Name: | Febuxostat |
|---|---|
| CAS No.: | 144060-53-7 |
| Molecular Structure: | |
 |
|
| Formula: | C16H16N2O3S |
| Molecular Weight: | 316.3748 |
| Synonyms: | 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-;Tei 6720;Febuxostat/ 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat (JAN/USAN);TMX 67;Tei-6720;2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid;TMX-67; |
| EINECS: | |
| Density: | 1.31 g/cm3 |
| Melting Point: | 238-239 °C |
| Boiling Point: | 536.6 °C at 760 mmHg |
| Flash Point: | 278.3 °C |
| Solubility: | |
| Appearance: | crystalline solid |
Details
| Name: | Febuxostat |
|---|---|
| CAS No.: | 144060-53-7 |
| Molecular Structure: | |
|
|
|
| Formula: | C16H16N2O3S |
| Molecular Weight: | 316.3748 |
| Synonyms: | 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-;Tei 6720;Febuxostat/ 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat (JAN/USAN);TMX 67;Tei-6720;2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid;TMX-67; |
| EINECS: | |
| Density: | 1.31 g/cm3 |
| Melting Point: | 238-239 °C |
| Boiling Point: | 536.6 °C at 760 mmHg |
| Flash Point: | 278.3 °C |
| Solubility: | |
| Appearance: |
crystalline solid |
|
Analytical Results |
||
|
Item |
Acceptance criteria |
Result |
|
Appearance |
White to almost white crystalline powder, odorless |
White crystalline powder, odorless |
|
Solubility |
Easily soluble in N,N-Dimethylformamide, soluble in Dimethyl sulfoxide. Sparingly soluble in Chloroform.Sligt soluble in methanol, practically insoluble in water |
Conforms |
|
m.p. |
207℃~211℃ |
207.5℃~208.5℃ |
|
Identification |
(1) In content test, principal peak in test solution is similar in retention time to reference. |
Conforms |
|
(2)UV:Max absorption at 215nm and 315nam, min absorption at 265nm |
Conforms |
|
|
(3)IR: Spectrum sample should be consistent with spectrum of reference standard |
Conforms |
|
|
Related substances |
ImpurityⅠNMT0.1% |
N.D. |
|
ImpurityⅡNMT0.1% |
N.D. |
|
|
ImpurityⅢNMT0.1% |
N.D. |
|
|
ImpurityⅣNMT0.1% |
0.02% |
|
|
Any other impurity NMT0.1% |
0.06% |
|
|
Total impurities: NMT 0.5%
|
0.11% |
|
|
Water |
≤2.0% |
0.5% |
|
Residue on ignition |
≤0.1% |
0.02% |
|
Heavy metals |
≤20ppm |
Conforms |
|
Residual Solvents |
Ethanol≤5000ppm |
23ppm |
|
Tetrahydrofuran≤720ppm |
N.D. |
|
|
N-hexane≤290ppm |
N.D. |
|
|
N,N-Dimethylformamide≤880ppm |
N.D. |
|
|
Dichloromethane≤600ppm |
24ppm |
|
|
Assay |
98.0%~102.0%（Calculated as anhydrous basis） |
99.2% |
